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This distribution pattern means AOD-9604 exerts its strongest effects precisely where intended (adipose tissue) with minimal effects elsewhere

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Because classic psychedelics rely primarily on 5-HT2A receptor activation to exert their acute and therapeutic effects, such receptor differences suggest that postmenopausal women may experience attenuated psychedelic effects or reduced 5-HT2A-mediated plasticity unless hormonal status, and potentially hormone therapy use, is considered